Best way to lock chests on a whole server

Right now I have world downloads from previous seasons of our SMP. We want to make museum worlds, and intend to put everyone in adventure mode. However, this does not stop them from opening up containers.

What would be the best way to achieve this, on a server wise scale? I feel like world guard would end up crashing because of how large the server is.
Solution
global region should do it just fine
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