SN1 or SN2
polar protic solvent ke respect mein SN1 or strong Nu- ke respect mein SN2, toh SN1 hoga ya SN2?
13 Replies
@Dexter
Note for OP
+solved @user1 @user2... to close the thread when your doubt is solved. Mention the users who helped you solve the doubt. This will be added to their stats.SN1
any reason?
might be because having a polar protic solvent interferes with the mechanism of Sn2 a lot
nevermind, actually
if there's H+ in the solution with nucleophile Nu, HNu might form instead of the thing we want
considering that a single positive hydrogen ion is probably one of the best targets for a nucleophile to ever exist because of literally zero steric hinderance
(speculation but you get the point)
KOH can be used for both SN1 and SN2, it depends on the substrate taken, here there is a possibility for a stable carbocation so I said SN1
Now if I were to take primary propanol or something, that time SN2 will take place
Pls correct me if I am wrong
so in secondary which will be preferred?
but like if we take alc KOH elimination happens while with aq.KOH substitution takes place that means even it is aq. but still it gives substiution rxn.
James Ashenhurst
Master Organic Chemistry
Deciding SN1/SN2/E1/E2 - The Solvent
With a secondary alkyl halide and a poorly basic but strong nucleophile in a polar aprotic solvent, expect SN2. If the nucleophile is a strong base, expect E2, regardless of solvent.
Check out the other bits (substrate, overall comparison)
Got it,Thank you sir!
+solved @iTeachChem @stormycloud @Nimboi
Post locked and archived successfully!
Archived by
<@1245771182104510557> (1245771182104510557)
Time
<t:1740840624:R>
Solved by
<@1035556259417571408> (1035556259417571408), <@821702877721657374> (821702877721657374), <@717724055217635398> (717724055217635398)