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@Dexter
Note for OP
+solved @user1 @user2... to close the thread when your doubt is solved. Mention the users who helped you solve the doubt. This will be added to their stats.Tertiary butoxide ion is a really strong base, pretty bad nucleophile
yeh tht i get but what is steric hind?
Steric hindrance
Basically,it's a very bulky group, and can't attack smaller or more cramped electrophilic centres
okkk
so can we say any bulky group will not act as nucleophile?
Have you studied Hoffman eliminations?
They can, but if they're better bases, they're worse nucleophiles. In general.
There are exceptions of course
oh boi
Aryl carbanion, though sterically hindered, is a good nucleophile, for example.
The thing you get from PhMgBr
i hvnt reached in tht
i dont recognize it
iteachchem
Transcription requested by Opt
the general thing is that anything I mean there are a lot of rules in organic chemistry right but the one rule that takes preference over everything else is steric hindrance if there is steric hindrance then stuff doesn't fly
iteachchem
Transcription requested by Opt
And since here the focus is, what do you call this? The nucleophile, not the substrate, right? So if it's bulky, it's not gonna move quickly because if you're talking about substrate, then you would talk about carbocation stability. But here nucleophile is the focus, right? So that's why this matters. So that specific type of nucleophilic substitution reaction where the, you know, how the ease of nucleophile attack matters, there this is gonna be a concern.
Aahhh okk okk so if we are talking about nucleophile in context we will see if it's easier to attack on substrate or not and based on that we will deduce?
In sn2
aahh ok ok
+solved @Opt @iTeachChem
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