Friedel craft rxn.
Why aniline, phenol doesn't undergo Friedel craft rxn. ,( ig they might go under vigorous conditions )unlike anisole as all exert +M
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@Dexter
Note for OP
+solved @user1 @user2... to close the thread when your doubt is solved. Mention the users who helped you solve the doubt. This will be added to their stats.Oh this is simple. This is just because the lone pairs are better electron centres for the electrophile to attack than benzene ring.
but why the lone pair of Anisole aren't better electron centres for the electrophile to attack than benzene ring
aniline has nh2 which is a very good erg , the electron on N of nh2 directly go on the lewis acid used making nr3+ which is a very good ewg does preventing eas
erg mtlb?
edg
Anisole can also have the electrophile attack on O, but, we need to disconnect another group from O to satisfy its valency, and both methyl and phenyl groups are worse leaving groups than whatever electrophile attacked.
also phenol does show FCR but products are very less
-H is poor/good leaving grp? wrt OH and NH2
matlab?
anisole ke case mein agar methyl aur phenyl r bad leaving grp toh phenol aur aniline ke case mein H kaise leaving grp h?
see the issue is alcl3
aniline and phenol dono main there is sm interaction with alcl3 which makes the catalyst less reactve.
aniline main lp coordinats with alcl3 which deactivates the ring instead of making it more reactive.
and for phenol, oh grp does hbonding and also interacts with alcl3. plus its already reactive enough for eas toh side rxn dominates
anisole is a chill dude and och3 doesn't interfere with alcl3 toh the rxn is possible
yeah this too, side rxns dominates
+solved @hardcoreisdead @itsav23
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