Advantage/Disadvantage of In and out edge vs one edge

I realize that the answer to this questions might be "it depends", but if I have a bunch of vertices labeled
A
and
B
and they always have an edge between them, is there any advantage either generically or in AWS Neptune to having an edge that is directed from
A
->
B
and a different edge directed
B
->
A
. Or is it just as good to have a single undirected edge (by whihic I mean use the both() step on the edge to ignore direction), and construct the traversal appropriately?

In this particular case, I will have relatively few
A
s very many
B
s
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